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Anti-Cleaved-Lamin A (D230) antibody

兔多抗 | 货号: ER60026


规格:
价格:RMB   2500
  • 概述

  • 产品描述 The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.
  • 产品名称 Anti-Cleaved-Lamin A (D230) antibody
  • 分子量 28/75 kDa
  • 种属反应性 Human,Mouse,Rat
  • 验证应用 WB,IHC
  • 抗体类型 兔多抗
  • 免疫原 The antiserum was produced against synthesized peptide derived from human Lamin A. AA range:181-230
  • 偶联 Non-conjugated
  • 性能

  • 形态 Liquid
  • 浓度 1 mg/mL.
  • 存放说明 Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • 存储缓冲液 Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 亚型 IgG
  • 纯化方式 Immunogen affinity purified.
  • 数据链接 SwissProt: P02545 Human
  • 其它名称 LMNA antibody; LMN1 antibody; Prelamin-A/C antibody;
  • 应用

    WB: 1:500-1:2000
    IHC: 1:100-1:300

  • 背景文献

  • 暂无
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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols