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KDM2A

小鼠单抗 | 货号: EM1712-20


规格:
价格:RMB   1500
  • 概述

  • 产品描述 This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants.
  • 产品名称 KDM2A
  • 分子量 132.8kDa
  • 种属反应性 Human
  • 验证应用 WB
  • 抗体类型 小鼠单抗
  • 免疫原 Purified recombinant fragment of human KDM2A (AA: 1-150) expressed in E. Coli.
  • 偶联 Non-conjugated
  • 性能

  • 形态 Liquid
  • 浓度 1 mg/mL
  • 存放说明 Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
  • 存储缓冲液 1*PBS with 0.05% sodium azide.
  • 亚型 IgG1
  • 纯化方式 Protein G purified.
  • 数据链接 SwissProt:Q9Y2K7 Human
  • 其它名称 [Histone-H3]-lysine-36 demethylase 1A antibody
    CXXC-type zinc finger protein 8 antibody
    CXXC8 antibody
    F box / LRR repeat protein 11 antibody
    F box and leucine rich repeat protein 11 antibody
    F box protein FBL7 antibody
    F-box and leucine-rich repeat protein 11 antibody
    F-box protein FBL7 antibody
    F-box protein Lilina antibody
    F-box/LRR-repeat protein 11 antibody
    FBL11 antibody
    FBL7 antibody
    FBXL11 antibody
    JHDM1A antibody
    JmjC domain-containing histone demethylation protein 1A antibody
    Jumonji C domain containing histone demethylase 1A antibody
    kdm2a antibody
    KDM2A_HUMAN antibody
    LILINA antibody
    Lysine (K) specific demethylase 2A antibody
    Lysine-specific demethylase 2A antibody
  • 应用

    WB: 1:500-1:2,000

  • Publishing research using KDM2A? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols